Ovarian cancer circulating extracelluar vesicles promote coagulation and have a potential in diagnosis: an iTRAQ based proteomic analysis.

Zhang, Wei; Peng, Peng; Ou, Xiaoxuan; Shen, Keng; Wu, Xiaohua

Zhang, Wei; Peng, Peng; Ou, Xiaoxuan; Shen, Keng; Wu, Xiaohua.

Afiliação

Zhang W; Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, 270 Dong-an Road, Shanghai, 200032, People's Republic of China.
Peng P; Department of Obstetrics and Gynecology Peking Union Medical College (PUMC) Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Ou X; Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, 270 Dong-an Road, Shanghai, 200032, People's Republic of China.
Shen K; Department of Obstetrics and Gynecology Peking Union Medical College (PUMC) Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. pumch_obgyn@126.com.
Wu X; Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, 270 Dong-an Road, Shanghai, 200032, People's Republic of China. docwuxh@hotmail.com.

BMC Cancer ; 19(1): 1095, 2019 Nov 12.

Article em En | MEDLINE | ID: mdl-31718609

Assuntos

Biomarcadores Tumorais; Coagulação Sanguínea; Carcinoma Epitelial do Ovário/metabolismo; Vesículas Extracelulares/metabolismo; Neoplasias Ovarianas/sangue; Neoplasias Ovarianas/metabolismo; Adulto; Idoso; Testes de Coagulação Sanguínea; Carcinoma Epitelial do Ovário/sangue; Carcinoma Epitelial do Ovário/diagnóstico; Cromatografia Líquida; Vesículas Extracelulares/ultraestrutura; Feminino; Humanos; Pessoa de Meia-Idade; Estadiamento de Neoplasias; Neoplasias Ovarianas/diagnóstico; Prognóstico; Proteoma; Proteômica/métodos; Curva ROC; Espectrometria de Massas em Tandem

Palavras-chave

Biomarker; Diagnosis; Epithelial ovarian cancer; Extracellular vesicles; Proteomics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Coagulação Sanguínea / Biomarcadores Tumorais / Vesículas Extracelulares / Carcinoma Epitelial do Ovário Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Adult / Aged / Female / Humans / Middle aged Idioma: En Revista: BMC Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article

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