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Chemogenetic activation of adrenocortical Gq signaling causes hyperaldosteronism and disrupts functional zonation.
Taylor, Matthew J; Ullenbruch, Matthew R; Frucci, Emily C; Rege, Juilee; Ansorge, Mark S; Gomez-Sanchez, Celso E; Begum, Salma; Laufer, Edward; Breault, David T; Rainey, William E.
Afiliação
  • Taylor MJ; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, USA.
  • Ullenbruch MR; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, USA.
  • Frucci EC; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, USA.
  • Rege J; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, USA.
  • Ansorge MS; The Sackler Institute for Developmental Psychobiology, Columbia University, New York, New York, USA.
  • Gomez-Sanchez CE; Endocrine Section, G.V. (Sonny) Montgomery VA Medical Center and the Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi, USA.
  • Begum S; Department of Obstetrics, Gynecology and Women's Health, Rutgers, The State University of New Jersey, Newark, New Jersey, USA.
  • Laufer E; Department of Human Genetics, University of Utah, Salt Lake City, Utah, USA.
  • Breault DT; Department of Pediatrics, Division of Endocrinology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Rainey WE; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, USA.
J Clin Invest ; 130(1): 83-93, 2020 01 02.
Article em En | MEDLINE | ID: mdl-31738186
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Zona Glomerulosa / Córtex Suprarrenal / Subunidades alfa Gq-G11 de Proteínas de Ligação ao GTP / Hiperaldosteronismo Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Revista: J Clin Invest Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Zona Glomerulosa / Córtex Suprarrenal / Subunidades alfa Gq-G11 de Proteínas de Ligação ao GTP / Hiperaldosteronismo Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Revista: J Clin Invest Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos