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Screening Human Embryos for Polygenic Traits Has Limited Utility.
Karavani, Ehud; Zuk, Or; Zeevi, Danny; Barzilai, Nir; Stefanis, Nikos C; Hatzimanolis, Alex; Smyrnis, Nikolaos; Avramopoulos, Dimitrios; Kruglyak, Leonid; Atzmon, Gil; Lam, Max; Lencz, Todd; Carmi, Shai.
Afiliação
  • Karavani E; Braun School of Public Health and Community Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
  • Zuk O; Department of Statistics, The Hebrew University of Jerusalem, Jerusalem 9190501, Israel.
  • Zeevi D; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Barzilai N; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Genetics, Institute for Aging Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Stefanis NC; Department of Psychiatry, National and Kapodistrian University of Athens Medical School, Eginition Hospital, 115 28 Athens, Greece; University Mental Health Research Institute, 115 27 Athens, Greece; Neurobiology Research Institute, Theodor-Theohari Cozzika Foundation, 115 21 Athens, Greece.
  • Hatzimanolis A; Department of Psychiatry, National and Kapodistrian University of Athens Medical School, Eginition Hospital, 115 28 Athens, Greece; Neurobiology Research Institute, Theodor-Theohari Cozzika Foundation, 115 21 Athens, Greece.
  • Smyrnis N; Department of Psychiatry, National and Kapodistrian University of Athens Medical School, Eginition Hospital, 115 28 Athens, Greece; University Mental Health Research Institute, 115 27 Athens, Greece.
  • Avramopoulos D; Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Kruglyak L; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Biological Chemistry, University of California, Los Angeles, Los Angeles, CA 90095, USA; Howard Hughes Medical Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Atzmon G; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Genetics, Institute for Aging Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Biology, Faculty of Natural Sciences, University of Haifa, Haifa 3498838, Israel.
  • Lam M; Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY 11004, USA; Institute of Behavioral Science, Feinstein Institutes of Medical Research, Manhasset, NY 11030, USA; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.
  • Lencz T; Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY 11004, USA; Institute of Behavioral Science, Feinstein Institutes of Medical Research, Manhasset, NY 11030, USA; Department of Psychiatry, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11549, USA. Electronic add
  • Carmi S; Braun School of Public Health and Community Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel. Electronic address: shai.carmi@huji.ac.il.
Cell ; 179(6): 1424-1435.e8, 2019 11 27.
Article em En | MEDLINE | ID: mdl-31761530
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Testes Genéticos / Herança Multifatorial / Embrião de Mamíferos Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Adult / Humans Idioma: En Revista: Cell Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Israel
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Testes Genéticos / Herança Multifatorial / Embrião de Mamíferos Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Adult / Humans Idioma: En Revista: Cell Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Israel