Trajectories of health-related quality of life in breast cancer patients.
Support Care Cancer
; 28(7): 3381-3389, 2020 Jul.
Article
em En
| MEDLINE
| ID: mdl-31768734
ABSTRACT
PURPOSE:
The purpose of this study was to explore the trajectory of health-related quality of life (HRQoL) and its predictors in breast cancer patients.METHODS:
A total of 126 women with newly diagnosed breast cancer provided baseline sociodemographic and medical characteristics and then completed an HRQoL questionnaire along with self-report measures of anxiety, depression, and cancer-related fatigue prior to their first cycle of chemotherapy (baseline), after chemotherapy completion, and at 6, and 12 months after chemotherapy completion. Group-based trajectory models were constructed to identify HRQoL trajectories over time. Logistic regression analysis was used to evaluate predictors of HRQoL in distinct patient groups.RESULTS:
Group-based trajectory modeling classified two patient groups participants with consistently medium overall HRQoL trajectories (41.1%) and participants with consistently low overall HRQoL trajectories (58.9%). Older age, perceived severe economic burden, and higher depression predicted consistently low overall HRQoL through 12 months after chemotherapy.CONCLUSIONS:
Less than half of the total number of patients maintained a medium level of overall HRQoL after diagnosis and treatment of breast cancer, and nearly 60% continued to have lower overall HRQoL even after the treatment was complete. Older participants with more severe economic burden and higher depression experienced lower and more persistent overall HRQoL; thus, these patients should be monitored and provided supportive care as a part of survivorship care.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ansiedade
/
Qualidade de Vida
/
Neoplasias da Mama
/
Depressão
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Qualitative_research
/
Risk_factors_studies
Limite:
Adult
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Female
/
Humans
Idioma:
En
Revista:
Support Care Cancer
Assunto da revista:
NEOPLASIAS
/
SERVICOS DE SAUDE
Ano de publicação:
2020
Tipo de documento:
Article