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Hb Phnom Penh Showing Falsely High or Reasonable HbA1c Values Depending on the Type of High-performance Liquid Chromatography System.
Hara, Kenji; Koga, Masafumi; Shinozaki, Hiroyuki; Yamauchi, Mototaka; Suzuki, Tatsuhiko; Naruse, Rika; Tsuchiya, Takafumi; Takebayashi, Kohzo; Inukai, Toshihiko; Hashimoto, Koshi.
Afiliação
  • Hara K; Department of Diabetes, Endocrinology and Hematology, Dokkyo Medical University Saitama Medical Center, Japan.
  • Koga M; Department of Internal Medicine, Hakuhokai Central Hospital, Japan.
  • Shinozaki H; Department of Diabetes, Endocrinology and Hematology, Dokkyo Medical University Saitama Medical Center, Japan.
  • Yamauchi M; Department of Diabetes, Endocrinology and Hematology, Dokkyo Medical University Saitama Medical Center, Japan.
  • Suzuki T; Department of Diabetes, Endocrinology and Hematology, Dokkyo Medical University Saitama Medical Center, Japan.
  • Naruse R; Department of Diabetes, Endocrinology and Hematology, Dokkyo Medical University Saitama Medical Center, Japan.
  • Tsuchiya T; Department of Diabetes, Endocrinology and Hematology, Dokkyo Medical University Saitama Medical Center, Japan.
  • Takebayashi K; Department of Diabetes, Endocrinology and Hematology, Dokkyo Medical University Saitama Medical Center, Japan.
  • Inukai T; Department of Diabetes, Endocrinology and Hematology, Dokkyo Medical University Saitama Medical Center, Japan.
  • Hashimoto K; Department of Diabetes, Endocrinology and Hematology, Dokkyo Medical University Saitama Medical Center, Japan.
Intern Med ; 59(6): 805-809, 2020 Mar 15.
Article em En | MEDLINE | ID: mdl-31787693
ABSTRACT
We herein report a 50-year-old Chinese woman with Hb Phnom Penh (α117Phe-Ile-α118Thr) showing high or reasonable HbA1c values depending on the type of high-performance liquid chromatography (HPLC) system. A high HbA1c value of 7.5% (HPLC assay G9) and a reasonable HbA1c value of 5.2% (assay unknown) were observed. Therefore, the patient was refereed to our hospital; the oral glucose tolerance test showed normal glucose tolerance. The HbA1c values measured by an enzymatic assay, immunoassay, and affinity assay, as well as most HPLC assays were within the reference range, whereas those measured by the Tosoh HPLC systems were high.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hemoglobinas Glicadas / Hemoglobinas Anormais / Cromatografia Líquida de Alta Pressão Tipo de estudo: Diagnostic_studies Limite: Female / Humans / Middle aged Idioma: En Revista: Intern Med Assunto da revista: MEDICINA INTERNA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hemoglobinas Glicadas / Hemoglobinas Anormais / Cromatografia Líquida de Alta Pressão Tipo de estudo: Diagnostic_studies Limite: Female / Humans / Middle aged Idioma: En Revista: Intern Med Assunto da revista: MEDICINA INTERNA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão