Genotyping of Human Papillomavirus in Cervical Squamous Intraepithelial Lesions in Mexican Women.
Jpn J Infect Dis
; 73(2): 157-160, 2020 Mar 24.
Article
em En
| MEDLINE
| ID: mdl-31787740
ABSTRACT
Approximately 40 genotypes of the human papillomavirus (HPV) have been identified in cervical mucosa. In particular, HPV-16 and HPV-18 have been associated with cervical neoplasia. Squamous intraepithelial lesions (SILs) are precursors of cervical cancer. This study aimed to identify the HPV by genotype in SILs using a linear array genotyping test in a population in Mexico. We performed a cross-sectional study of 129 female patients with or without SILs, as determined by colposcopy, who completed a risk factor questionnaire. Cervical swab samples were obtained and genotyped using a Linear Array HPV Genotyping assay. Forty-nine (37.98%) samples were positive for HPV, and 24 genotypes were identified among these samples. The most common genotype was HPV-16. Twelve genotypes were found in both high- and low-grade SILs (HPV-6, 16, 31, 39, 51, 52, 53, 58, 59, 61, 67, and 84), of which seven were high-risk SILs (HPV-16, 31, 39, 51, 52, 58, and 59). Among the populations studied, the most frequent genotype was HPV-16, multiple infections were found, and four patients without injury tested positive for HPV.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Papillomaviridae
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Displasia do Colo do Útero
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Infecções por Papillomavirus
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Lesões Intraepiteliais Escamosas
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prevalence_studies
/
Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Female
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Humans
País/Região como assunto:
Mexico
Idioma:
En
Revista:
Jpn J Infect Dis
Assunto da revista:
DOENCAS TRANSMISSIVEIS
Ano de publicação:
2020
Tipo de documento:
Article