Live-Cell Sensing of Telomerase Activity by Using Hybridization-Sensitive Fluorescent Oligonucleotide Probes.

Chen, Jiazhuo; Morihiro, Kunihiko; Fukui, Daisuke; Guo, Lihao; Okamoto, Akimitsu

Chen, Jiazhuo; Morihiro, Kunihiko; Fukui, Daisuke; Guo, Lihao; Okamoto, Akimitsu.

Afiliação

Chen J; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Morihiro K; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Fukui D; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Guo L; Research Center for Advanced Science and Technology (RCAST), The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo, 153-8904, Japan.
Okamoto A; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.

Chembiochem ; 21(7): 1022-1027, 2020 04 01.

Article em En | MEDLINE | ID: mdl-31840916

Assuntos

Corantes Fluorescentes/química; Sondas de Oligonucleotídeos/metabolismo; Telomerase/metabolismo; Sequência de Bases; Células HeLa; Humanos; Microscopia Confocal; Hibridização de Ácido Nucleico; Sondas de Oligonucleotídeos/química

Palavras-chave

drug discovery; fluorescence; imaging agents; oligonucleotides; telomerase

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sondas de Oligonucleotídeos / Telomerase / Corantes Fluorescentes Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Chembiochem Assunto da revista: BIOQUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão

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