NSCLC Mutated Isoforms of CCDC6 Affect the Intracellular Distribution of the Wild Type Protein Promoting Cisplatinum Resistance and PARP Inhibitors Sensitivity in Lung Cancer Cells.

Cerrato, Aniello; Morra, Francesco; Di Domenico, Imma; Celetti, Angela

Cerrato, Aniello; Morra, Francesco; Di Domenico, Imma; Celetti, Angela.

Afiliação

Cerrato A; Institute for the Experimental Endocrinology and Oncology "Gaetano Salvatore", Italian National Council of Research, Via S. Pansini 5, 80131 Naples, Italy.
Morra F; Institute for the Experimental Endocrinology and Oncology "Gaetano Salvatore", Italian National Council of Research, Via S. Pansini 5, 80131 Naples, Italy.
Di Domenico I; Institute for the Experimental Endocrinology and Oncology "Gaetano Salvatore", Italian National Council of Research, Via S. Pansini 5, 80131 Naples, Italy.
Celetti A; Institute for the Experimental Endocrinology and Oncology "Gaetano Salvatore", Italian National Council of Research, Via S. Pansini 5, 80131 Naples, Italy.

Cancers (Basel) ; 12(1)2019 Dec 21.

Article em En | MEDLINE | ID: mdl-31877762

Palavras-chave

BRCAlike; CCDC6; DNA-damage-repair; PARP-1-inhibitors-sensitivity; biomarker; cell-cycle-checkpoint; dominant-negative; homologous-recombination; synthetic-lethal; targeted-therapy

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Revista: Cancers (Basel) Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Itália

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