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Experimental Abdominal Sepsis: Sticking to an Awkward but Still Useful Translational Model.
Murando, Federica; Peloso, Andrea; Cobianchi, Lorenzo.
Afiliação
  • Murando F; General Surgery Department, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
  • Peloso A; Hepatology and Transplantation Laboratory, Department of Surgery, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
  • Cobianchi L; Divisions of Abdominal and Transplantation Surgery, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland.
Mediators Inflamm ; 2019: 8971036, 2019.
Article em En | MEDLINE | ID: mdl-31885502
ABSTRACT
Animal models are widely used to replicate human intra-abdominal infections. Different methodologies have been described and proposed in the scientific literature, including injection and surgical models. The aim of this review is to recapitulate the advantages and disadvantages of each method to help choose the most appropriate model for individual experimental purposes.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sepse / Modelos Animais de Doenças Limite: Animals / Humans Idioma: En Revista: Mediators Inflamm Assunto da revista: BIOQUIMICA / PATOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Itália

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sepse / Modelos Animais de Doenças Limite: Animals / Humans Idioma: En Revista: Mediators Inflamm Assunto da revista: BIOQUIMICA / PATOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Itália