Attenuation of Wnt/ß-catenin signaling in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis.

Chen, Chun-Bing; Chang, Wan-Chun; Wu, Ming-Ying; Kao, Tzu-Yang; Wang, Ying-Wen; Wang, Chuang Wei; Chen, Chi-Ju; Chung, Wen-Hung; Su, Shih-Chi

Chen, Chun-Bing; Chang, Wan-Chun; Wu, Ming-Ying; Kao, Tzu-Yang; Wang, Ying-Wen; Wang, Chuang Wei; Chen, Chi-Ju; Chung, Wen-Hung; Su, Shih-Chi.

Afiliação

Chen CB; Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospitals, Linkou, Taipei, and Keelung, Taiwan.
Chang WC; Whole-Genome Research Core Laboratory of Human Diseases, Chang Gung Memorial Hospital, Keelung, Taiwan.
Wu MY; Chang Gung Immunology Consortium, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan.
Kao TY; College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Wang YW; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Wang CW; Immune-Oncology Center of Excellence, Chang Gung Memorial Hospital, Linkou, Taiwan.
Chen CJ; Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospitals, Linkou, Taipei, and Keelung, Taiwan.
Chung WH; Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospitals, Linkou, Taipei, and Keelung, Taiwan.
Su SC; College of Medicine, Chang Gung University, Taoyuan, Taiwan.

Int J Biol Sci ; 16(2): 353-364, 2020.

Article em En | MEDLINE | ID: mdl-31929762

Assuntos

Síndrome de Stevens-Johnson/tratamento farmacológico; Síndrome de Stevens-Johnson/metabolismo; Via de Sinalização Wnt/fisiologia; Adolescente; Adulto; Idoso; Idoso de 80 Anos ou mais; Criança; Pré-Escolar; Feminino; Predisposição Genética para Doença/genética; Humanos; Fator 1 de Ligação ao Facilitador Linfoide/metabolismo; Masculino; Pessoa de Meia-Idade; Pele; Fator 1 de Transcrição de Linfócitos T/metabolismo; Linfócitos T/metabolismo; Via de Sinalização Wnt/genética; Adulto Jovem

Palavras-chave

Stevens-Johnson syndrome (SJS); T cell factor-1 (TCF-1); Wnt; cytotoxic T lymphocyte (CTL); lymphoid enhancer binding factor 1 (LEF-1).; toxic epidermal necrosis (TEN)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome de Stevens-Johnson / Via de Sinalização Wnt Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Biol Sci Assunto da revista: BIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Taiwan

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