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LKB1 Represses ATOH1 via PDK4 and Energy Metabolism and Regulates Intestinal Stem Cell Fate.
Gao, Yajing; Yan, Yan; Tripathi, Sushil; Pentinmikko, Nalle; Amaral, Ana; Päivinen, Pekka; Domènech-Moreno, Eva; Andersson, Simon; Wong, Iris P L; Clevers, Hans; Katajisto, Pekka; Mäkelä, Tomi P.
Afiliação
  • Gao Y; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Finland; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Finland.
  • Yan Y; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Finland; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Finland. Electronic address: yany@mskcc.org.
  • Tripathi S; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Finland; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Finland.
  • Pentinmikko N; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Finland; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Finland; Institute of Biotechnology, HiLIFE, University of Helsinki, Finland.
  • Amaral A; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.
  • Päivinen P; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Finland; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Finland.
  • Domènech-Moreno E; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Finland; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Finland.
  • Andersson S; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Finland; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Finland; Institute of Biotechnology, HiLIFE, University of Helsinki, Finland.
  • Wong IPL; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Finland.
  • Clevers H; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and Cancer Genomics Netherlands, University Medical Center Utrecht and Princess Máxima Centre, Utrecht, The Netherlands.
  • Katajisto P; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Finland; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Finland; Institute of Biotechnology, HiLIFE, University of Helsinki, Finland; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm
  • Mäkelä TP; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Finland; HiLIFE-Helsinki Institute of Life Science, University of Helsinki, Finland. Electronic address: tomi.makela@helsinki.fi.
Gastroenterology ; 158(5): 1389-1401.e10, 2020 04.
Article em En | MEDLINE | ID: mdl-31930988
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco / Proteínas Serina-Treonina Quinases / Metabolismo Energético / Fatores de Transcrição Hélice-Alça-Hélice Básicos / Piruvato Desidrogenase Quinase de Transferência de Acetil Limite: Animals / Humans Idioma: En Revista: Gastroenterology Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Finlândia
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco / Proteínas Serina-Treonina Quinases / Metabolismo Energético / Fatores de Transcrição Hélice-Alça-Hélice Básicos / Piruvato Desidrogenase Quinase de Transferência de Acetil Limite: Animals / Humans Idioma: En Revista: Gastroenterology Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Finlândia