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Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment.
Kregel, Steven; Wang, Chao; Han, Xin; Xiao, Lanbo; Fernandez-Salas, Ester; Bawa, Pushpinder; McCollum, Brooke L; Wilder-Romans, Kari; Apel, Ingrid J; Cao, Xuhong; Speers, Corey; Wang, Shaomeng; Chinnaiyan, Arul M.
Afiliação
  • Kregel S; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
  • Wang C; Departments of Internal Medicine, Pharmacology, and Medicinal Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.
  • Han X; Departments of Internal Medicine, Pharmacology, and Medicinal Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.
  • Xiao L; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
  • Fernandez-Salas E; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Departments of Internal Medicine, Pharmacology, and Medicinal Chemistry, University of Michigan, Ann Arbor, MI 48109, U
  • Bawa P; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
  • McCollum BL; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Wilder-Romans K; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Apel IJ; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
  • Cao X; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
  • Speers C; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Departments of Internal Medicine, Pharmacology, and Medicinal Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.
  • Wang S; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Departments of Internal Medicine, Pharmacology, and Medicinal Chemistry, University of Michigan, Ann Arbor, MI 48109, U
  • Chinnaiyan AM; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Urology, University of Michiga
Neoplasia ; 22(2): 111-119, 2020 02.
Article em En | MEDLINE | ID: mdl-31931431
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Androgênicos / Antagonistas de Receptores de Andrógenos / Neoplasias de Próstata Resistentes à Castração / Androgênios Limite: Animals / Humans / Male Idioma: En Revista: Neoplasia Assunto da revista: NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Androgênicos / Antagonistas de Receptores de Andrógenos / Neoplasias de Próstata Resistentes à Castração / Androgênios Limite: Animals / Humans / Male Idioma: En Revista: Neoplasia Assunto da revista: NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos