Pharmacodynamic Effects of Vorapaxar in Patients With and Without Diabetes Mellitus: Results of the OPTIMUS-5 Study.

Franchi, Francesco; Rollini, Fabiana; Kairouz, Victor; Rivas Rios, Jose; Rivas, Andrea; Agarwal, Malhar; Briceno, Maryuri; Wali, Mustafa; Nawaz, Ahmed; Silva, Gabriel; Shaikh, Zubair; Maaliki, Naji; Been, Latonya; Piraino, Jason; Pineda, Andres M; Suryadevara, Siva; Soffer, Daniel; Zenni, Martin M; Jennings, Lisa K; Bass, Theodore A; Angiolillo, Dominick J

Pharmacodynamic Effects of Vorapaxar in Patients With and Without Diabetes Mellitus: Results of the OPTIMUS-5 Study.

Franchi, Francesco; Rollini, Fabiana; Kairouz, Victor; Rivas Rios, Jose; Rivas, Andrea; Agarwal, Malhar; Briceno, Maryuri; Wali, Mustafa; Nawaz, Ahmed; Silva, Gabriel; Shaikh, Zubair; Maaliki, Naji; Been, Latonya; Piraino, Jason; Pineda, Andres M; Suryadevara, Siva; Soffer, Daniel; Zenni, Martin M; Jennings, Lisa K; Bass, Theodore A; Angiolillo, Dominick J.

Afiliação

Franchi F; Division of Cardiology, Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.
Rollini F; Division of Cardiology, Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.
Kairouz V; Division of Cardiology, Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.
Rivas Rios J; Division of Cardiology, Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.
Rivas A; Division of Cardiology, Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.
Agarwal M; Division of Cardiology, Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.
Briceno M; Division of Cardiology, Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.
Wali M; Division of Cardiology, Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.
Nawaz A; Division of Cardiology, Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.
Silva G; Division of Cardiology, Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.
Shaikh Z; Division of Cardiology, Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.
Maaliki N; Division of Cardiology, Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.
Been L; Division of Cardiology, Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.
Piraino J; Division of Foot and Ankle, Department of Orthopaedic Surgery and Rehabilitation, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.
Pineda AM; Division of Cardiology, Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.
Suryadevara S; Division of Cardiology, Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.
Soffer D; Division of Cardiology, Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.
Zenni MM; Division of Cardiology, Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.
Jennings LK; CirQuest Labs, Memphis, Tennessee.
Bass TA; Division of Cardiology, Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.
Angiolillo DJ; Division of Cardiology, Department of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida.

JACC Basic Transl Sci ; 4(7): 763-775, 2019 Nov.

Article em En | MEDLINE | ID: mdl-31998847

Palavras-chave

ADP, adenosine diphosphate; CAT, collagen-related peptide + adenosine diphosphate + thrombin receptor activating peptide; CI, confidence interval; COX, cyclooxygenase; DAPT, dual antiplatelet therapy; DM, diabetes mellitus; LTA, light transmittance aggregometry; MI, myocardial infarction; MPA, maximum platelet aggregation; PAD, peripheral arterial disease; PAR, protease-activated receptor; PD, pharmacodynamic; TRAP, thrombin receptor activating peptide; TXB2, thromboxane B2; VASP, vasodilator-stimulated phosphoprotein; dual antiplatelet therapy; o.d., once daily; pharmacodynamics; platelets; thrombin; vorapaxar

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: JACC Basic Transl Sci Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: JACC Basic Transl Sci Ano de publicação: 2019 Tipo de documento: Article