Visible-light-driven metal-free aerobic synthesis of highly diastereoselective phosphinoylpyrroloindoles.
Org Biomol Chem
; 18(7): 1354-1358, 2020 Feb 21.
Article
em En
| MEDLINE
| ID: mdl-31999293
ABSTRACT
A visible-light-driven metal-free phosphorus radical mediated construction of 2-phosphinoyl-3H-pyrrolo[1,2,a]indoles is described. This mild tandem phosphinoylation/cyclization protocol utilizes air as a green oxidant and proceeds in a short span of time at room temperature with high functional group tolerance, and excellent chemo- and diastereoselectivity.
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Base de dados:
MEDLINE
Idioma:
En
Revista:
Org Biomol Chem
Assunto da revista:
BIOQUIMICA
/
QUIMICA
Ano de publicação:
2020
Tipo de documento:
Article