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Tranylcypromine-Based LSD1 Inhibitors: Structure-Activity Relationships, Antiproliferative Effects in Leukemia, and Gene Target Modulation.
Fioravanti, Rossella; Romanelli, Annalisa; Mautone, Nicola; Di Bello, Elisabetta; Rovere, Annarita; Corinti, Davide; Zwergel, Clemens; Valente, Sergio; Rotili, Dante; Botrugno, Oronza A; Dessanti, Paola; Vultaggio, Stefania; Vianello, Paola; Cappa, Anna; Binda, Claudia; Mattevi, Andrea; Minucci, Saverio; Mercurio, Ciro; Varasi, Mario; Mai, Antonello.
Afiliação
  • Fioravanti R; Department of Drug Chemistry and Technologies, Sapienza University of Rome, P. le A. Moro 5, 00185, Rome, Italy.
  • Romanelli A; Department of Drug Chemistry and Technologies, Sapienza University of Rome, P. le A. Moro 5, 00185, Rome, Italy.
  • Mautone N; Department of Drug Chemistry and Technologies, Sapienza University of Rome, P. le A. Moro 5, 00185, Rome, Italy.
  • Di Bello E; Department of Drug Chemistry and Technologies, Sapienza University of Rome, P. le A. Moro 5, 00185, Rome, Italy.
  • Rovere A; Department of Drug Chemistry and Technologies, Sapienza University of Rome, P. le A. Moro 5, 00185, Rome, Italy.
  • Corinti D; Department of Drug Chemistry and Technologies, Sapienza University of Rome, P. le A. Moro 5, 00185, Rome, Italy.
  • Zwergel C; Department of Drug Chemistry and Technologies, Sapienza University of Rome, P. le A. Moro 5, 00185, Rome, Italy.
  • Valente S; Department of Medicine of Precision, University of Studi della Campania Luigi Vanvitelli, Vico L. De Crecchio 7, 80138, Naples, Italy.
  • Rotili D; Department of Drug Chemistry and Technologies, Sapienza University of Rome, P. le A. Moro 5, 00185, Rome, Italy.
  • Botrugno OA; Department of Drug Chemistry and Technologies, Sapienza University of Rome, P. le A. Moro 5, 00185, Rome, Italy.
  • Dessanti P; Department of Experimental Oncology, IEO - European Institute of Oncology IRCCS, via Adamello 16, 20139, Milan, Italy.
  • Vultaggio S; IRCCS San Raffaele Scientific Institute, Via Olgettina Milano, 58, 20132, Milan, Italy.
  • Vianello P; Department of Experimental Oncology, IEO - European Institute of Oncology IRCCS, via Adamello 16, 20139, Milan, Italy.
  • Cappa A; Oryzon Genomics S.A., Sant Ferran, 08940 Cornellà de Llobregat, Barcelona, Spain.
  • Binda C; Department of Experimental Oncology, IEO - European Institute of Oncology IRCCS, via Adamello 16, 20139, Milan, Italy.
  • Mattevi A; Department of Experimental Oncology, IEO - European Institute of Oncology IRCCS, via Adamello 16, 20139, Milan, Italy.
  • Minucci S; Department of Experimental Oncology, IEO - European Institute of Oncology IRCCS, via Adamello 16, 20139, Milan, Italy.
  • Mercurio C; Experimental Therapeutics Program, IFOM-FIRC Institute of Molecular Oncology Foundation, via Adamello 16, 20139, Milan, Italy.
  • Varasi M; Department of Biology and Biotechnology, University of Pavia, Via Ferrata 9, 27100, Pavia, Italy.
  • Mai A; Department of Biology and Biotechnology, University of Pavia, Via Ferrata 9, 27100, Pavia, Italy.
ChemMedChem ; 15(7): 643-658, 2020 04 03.
Article em En | MEDLINE | ID: mdl-32003940
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tranilcipromina / Inibidores Enzimáticos / Histona Desmetilases / Antineoplásicos Limite: Humans Idioma: En Revista: ChemMedChem Assunto da revista: FARMACOLOGIA / QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Itália
Texto completo
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tranilcipromina / Inibidores Enzimáticos / Histona Desmetilases / Antineoplásicos Limite: Humans Idioma: En Revista: ChemMedChem Assunto da revista: FARMACOLOGIA / QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Itália