Eriocalyxin B induces apoptosis in human triple negative breast cancer cells via inhibiting STAT3 activation and mitochondrial dysfunction.

Riaz, Ammara; Rasul, Azhar; Hussain, Ghulam; Zubair, Muhammad; Samiullah, Khizar; Sarfraz, Iqra; Masood, Muqaddas; Jabeen, Farhat; Sultana, Tayyaba; Sultana, Salma

Riaz, Ammara; Rasul, Azhar; Hussain, Ghulam; Zubair, Muhammad; Samiullah, Khizar; Sarfraz, Iqra; Masood, Muqaddas; Jabeen, Farhat; Sultana, Tayyaba; Sultana, Salma.

Afiliação

Riaz A; Department of Zoology, Government College University Faisalabad, Punjab Pakistan.
Rasul A; Department of Zoology, Government College University Faisalabad, Punjab Pakistan.
Hussain G; Department of Physiology, Government College University Faisalabad, Punjab Pakistan.
Zubair M; Department of Bioinformatics and Biotechnology, Government College University Faisalabad, Punjab Pakistan.
Samiullah K; Department of Zoology, Government College University Faisalabad, Punjab Pakistan.
Sarfraz I; Department of Zoology, Government College University Faisalabad, Punjab Pakistan.
Masood M; The Key Laboratory of Molecular Epigenetics of MOE, Institute of Genetics and Cytology, Northeast Normal University, Changchun, China.
Jabeen F; Department of Zoology, Government College University Faisalabad, Punjab Pakistan.
Sultana T; Department of Zoology, Government College University Faisalabad, Punjab Pakistan.
Sultana S; Department of Zoology, Government College University Faisalabad, Punjab Pakistan.

Pak J Pharm Sci ; 32(6(Supplementary)): 2843-2848, 2019 Nov.

Article em En | MEDLINE | ID: mdl-32024623

Assuntos

Antineoplásicos Fitogênicos/farmacologia; Diterpenos/farmacologia; Mitocôndrias/efeitos dos fármacos; Doenças Mitocondriais/tratamento farmacológico; Fator de Transcrição STAT3/antagonistas & inibidores; Neoplasias de Mama Triplo Negativas/tratamento farmacológico; Apoptose/efeitos dos fármacos; Caspase 3/metabolismo; Linhagem Celular Tumoral; Proliferação de Células/efeitos dos fármacos; Feminino; Humanos; Células MCF-7; Mitocôndrias/metabolismo; Doenças Mitocondriais/metabolismo; NF-kappa B/metabolismo; Proteínas Proto-Oncogênicas c-bcl-2/metabolismo; Transdução de Sinais/efeitos dos fármacos; Neoplasias de Mama Triplo Negativas/metabolismo

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Base de dados: MEDLINE Assunto principal: Doenças Mitocondriais / Diterpenos / Fator de Transcrição STAT3 / Neoplasias de Mama Triplo Negativas / Mitocôndrias / Antineoplásicos Fitogênicos Limite: Female / Humans Idioma: En Revista: Pak J Pharm Sci Assunto da revista: FARMACIA / FARMACOLOGIA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article

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