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Generation of mouse model of TGFBI-R124C corneal dystrophy using CRISPR/Cas9-mediated homology-directed repair.
Kitamoto, Kohdai; Taketani, Yukako; Fujii, Wataru; Inamochi, Aya; Toyono, Tetsuya; Miyai, Takashi; Yamagami, Satoru; Kuroda, Masahiko; Usui, Tomohiko; Ouchi, Yasuo.
Afiliação
  • Kitamoto K; Department of Ophthalmology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
  • Taketani Y; Department of Ophthalmology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
  • Fujii W; Schepens Eye Research Institute, Boston, MA, USA.
  • Inamochi A; Graduate School of Agricultural and Life Sciences, University of Tokyo, Tokyo, Japan.
  • Toyono T; Department of Ophthalmology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
  • Miyai T; Department of Ophthalmology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
  • Yamagami S; Department of Ophthalmology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
  • Kuroda M; Department of Ophthalmology, Nihon University, Tokyo, Japan.
  • Usui T; Department of Molecular Pathology, Tokyo Medical University, Tokyo, Japan.
  • Ouchi Y; Department of Ophthalmology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan. tomohiko-tky@umin.ac.jp.
Sci Rep ; 10(1): 2000, 2020 02 06.
Article em En | MEDLINE | ID: mdl-32029872
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Distrofias Hereditárias da Córnea / Proteínas da Matriz Extracelular / Fator de Crescimento Transformador beta / Modelos Animais de Doenças Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Distrofias Hereditárias da Córnea / Proteínas da Matriz Extracelular / Fator de Crescimento Transformador beta / Modelos Animais de Doenças Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão