Efficacy & safety of Carica papaya leaf extract (CPLE) in severe thrombocytopenia (&#8804;30,000/µl) in adult dengue - Results of a pilot study.

Sathyapalan, Dipu T; Padmanabhan, Athira; Moni, Merlin; P-Prabhu, Binny; Prasanna, Preetha; Balachandran, Sabarish; Trikkur, Sreekrishnan P; Jose, Soumya; Edathadathil, Fabia; Anilkumar, Jagan O; Jayaprasad, Rekha; Koramparambil, Gireeshkumar; Kamath, Ravindra C; Menon, Veena; Menon, Vidya

Efficacy & safety of Carica papaya leaf extract (CPLE) in severe thrombocytopenia (≤30,000/µl) in adult dengue - Results of a pilot study.

Sathyapalan, Dipu T; Padmanabhan, Athira; Moni, Merlin; P-Prabhu, Binny; Prasanna, Preetha; Balachandran, Sabarish; Trikkur, Sreekrishnan P; Jose, Soumya; Edathadathil, Fabia; Anilkumar, Jagan O; Jayaprasad, Rekha; Koramparambil, Gireeshkumar; Kamath, Ravindra C; Menon, Veena; Menon, Vidya.

Afiliação

Sathyapalan DT; Department of General Medicine, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Padmanabhan A; Clinical Virology Laboratory, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Moni M; Department of General Medicine, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
P-Prabhu B; Department of General Medicine, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Prasanna P; Department of Medical Administration, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Balachandran S; Department of Emergency Medicine, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Trikkur SP; Department of Emergency Medicine, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Jose S; Clinical Virology Laboratory, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Edathadathil F; Department of Allied Health Sciences, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Anilkumar JO; Clinical Virology Laboratory, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Jayaprasad R; Department of Medical Administration, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Koramparambil G; Department of Emergency Medicine, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Kamath RC; Department of Integrated & Holistic Medicine, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Menon V; Clinical Virology Laboratory, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Menon V; Department of General Medicine, Amrita Institute of Medical Sciences, Kochi, Kerala, India.

PLoS One ; 15(2): e0228699, 2020.

Article em En | MEDLINE | ID: mdl-32074143

Assuntos

Carica/química; Dengue/complicações; Extratos Vegetais/farmacologia; Folhas de Planta/química; Segurança; Trombocitopenia/complicações; Trombocitopenia/tratamento farmacológico; Adulto; Estudos de Coortes; Citocinas/metabolismo; Feminino; Hematócrito; Humanos; Tempo de Internação; Masculino; Pessoa de Meia-Idade; Projetos Piloto; Extratos Vegetais/efeitos adversos; Extratos Vegetais/uso terapêutico; Contagem de Plaquetas; Trombocitopenia/sangue; Trombocitopenia/metabolismo; Resultado do Tratamento; Proteínas não Estruturais Virais/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Segurança / Trombocitopenia / Extratos Vegetais / Folhas de Planta / Carica / Dengue Tipo de estudo: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Índia

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