The COP9 signalosome mediates the Spt23 regulated fatty acid desaturation and ergosterol biosynthesis.

Sinha, Abhishek; Israeli, Ran; Cirigliano, Angela; Gihaz, Shalev; Trabelcy, Beny; Braus, Gerhard H; Gerchman, Yoram; Fishman, Ayelet; Negri, Rodolfo; Rinaldi, Teresa; Pick, Elah

Sinha, Abhishek; Israeli, Ran; Cirigliano, Angela; Gihaz, Shalev; Trabelcy, Beny; Braus, Gerhard H; Gerchman, Yoram; Fishman, Ayelet; Negri, Rodolfo; Rinaldi, Teresa; Pick, Elah.

Afiliação

Sinha A; Department of Biology and Environment, Faculty of Natural Sciences, University of Haifa, Oranim, Israel.
Israeli R; Department of Biology and Environment, Faculty of Natural Sciences, University of Haifa, Oranim, Israel.
Cirigliano A; Department of Biology and Biotechnology "Charles Darwin", Sapienza University of Rome, Rome, Italy.
Gihaz S; Department of Biotechnology and Food Engineering, Technion-Israel Institute of Technology, Haifa, Israel.
Trabelcy B; Department of Biology and Environment, Faculty of Natural Sciences, University of Haifa, Oranim, Israel.
Braus GH; Department of Molecular Microbiology and Genetics, Institute of Microbiology and Genetics, Goettingen Center for Molecular Biosciences (GZMB), University of Goettingen, Goettingen, Germany.
Gerchman Y; Department of Biology and Environment, Faculty of Natural Sciences, University of Haifa, Oranim, Israel.
Fishman A; Department of Biotechnology and Food Engineering, Technion-Israel Institute of Technology, Haifa, Israel.
Negri R; Department of Biology and Biotechnology "Charles Darwin", Sapienza University of Rome, Rome, Italy.
Rinaldi T; Department of Biology and Biotechnology "Charles Darwin", Sapienza University of Rome, Rome, Italy.
Pick E; Department of Biology and Environment, Faculty of Natural Sciences, University of Haifa, Oranim, Israel.

FASEB J ; 34(4): 4870-4889, 2020 04.

Article em En | MEDLINE | ID: mdl-32077151

Assuntos

Complexo do Signalossomo COP9/metabolismo; Ergosterol/biossíntese; Ácidos Graxos Insaturados/metabolismo; Proteínas de Membrana/metabolismo; Metaloendopeptidases/metabolismo; Proteínas de Saccharomyces cerevisiae/metabolismo; Fatores de Transcrição/metabolismo; Complexo do Signalossomo COP9/genética; Estresse do Retículo Endoplasmático; Ergosterol/genética; Ácidos Graxos Insaturados/genética; Deleção de Genes; Gotículas Lipídicas/metabolismo; Proteínas de Membrana/genética; Metaloendopeptidases/genética; Saccharomyces cerevisiae; Proteínas de Saccharomyces cerevisiae/genética; Fatores de Transcrição/genética

Palavras-chave

S. cerevisiae; COP9 signalosome; Csn5; Ergosterol; NEDD8; Ole1; Rub1; Spt23

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Metaloendopeptidases / Proteínas de Saccharomyces cerevisiae / Ergosterol / Ácidos Graxos Insaturados / Complexo do Signalossomo COP9 / Proteínas de Membrana Tipo de estudo: Prognostic_studies Idioma: En Revista: FASEB J Assunto da revista: BIOLOGIA / FISIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Israel

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