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Chronic virus infection drives CD8 T cell-mediated thymic destruction and impaired negative selection.
Elsaesser, Heidi J; Mohtashami, Mahmood; Osokine, Ivan; Snell, Laura M; Cunningham, Cameron R; Boukhaled, Giselle M; McGavern, Dorian B; Zúñiga-Pflücker, Juan Carlos; Brooks, David G.
Afiliação
  • Elsaesser HJ; Princess Margaret Cancer Center, University Health Network, Toronto, ON M5G 2M9, Canada.
  • Mohtashami M; Department of Immunology, University of Toronto, Toronto, ON M5S 1A8 Canada.
  • Osokine I; Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.
  • Snell LM; Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095.
  • Cunningham CR; Princess Margaret Cancer Center, University Health Network, Toronto, ON M5G 2M9, Canada.
  • Boukhaled GM; Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095.
  • McGavern DB; Princess Margaret Cancer Center, University Health Network, Toronto, ON M5G 2M9, Canada.
  • Zúñiga-Pflücker JC; Viral Immunology and Intravital Imaging Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20824.
  • Brooks DG; Princess Margaret Cancer Center, University Health Network, Toronto, ON M5G 2M9, Canada.
Proc Natl Acad Sci U S A ; 117(10): 5420-5429, 2020 03 10.
Article em En | MEDLINE | ID: mdl-32094187
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Timo / Interferon Tipo I / Linfócitos T CD8-Positivos / Coriomeningite Linfocítica / Vírus da Coriomeningite Linfocítica Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Timo / Interferon Tipo I / Linfócitos T CD8-Positivos / Coriomeningite Linfocítica / Vírus da Coriomeningite Linfocítica Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Canadá