Towards Precision Medicine in Systemic Lupus Erythematosus.
Pharmgenomics Pers Med
; 13: 39-49, 2020.
Article
em En
| MEDLINE
| ID: mdl-32099443
ABSTRACT
Systemic lupus erythematosus (SLE) is a remarkable condition characterised by diversity amongst its clinical features and immunological abnormalities. In this review, we attempt to capture the major immunological changes linked to the pathophysiology of lupus and discuss the challenge it presents in moving towards the concept of precision medicine. Currently broadly similar types of drugs, e.g., steroids, immunosuppressives, hydroxychloroquine are used to treat many of the diverse clinical features of SLE. We suspect that, as the precise immunopathological abnormalities differ between the various organs/systems in lupus patients, it will be some time before precision medicine can be fully applied to SLE.
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Base de dados:
MEDLINE
Idioma:
En
Revista:
Pharmgenomics Pers Med
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Reino Unido