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Distinct Mechanisms of Dissemination of NDM-1 Metallo-ß-Lactamase in Acinetobacter Species in Argentina.
Adams, Mark D; Pasteran, Fernando; Traglia, German M; Martinez, Jasmine; Huang, Fanny; Liu, Christine; Fernandez, Jennifer S; Lopez, Carolina; Gonzalez, Lisandro J; Albornoz, Ezequiel; Corso, Alejandra; Vila, Alejandro J; Bonomo, Robert A; Ramirez, Maria Soledad.
Afiliação
  • Adams MD; The Jackson Laboratory, Farmington, Connecticut, USA.
  • Pasteran F; National/Regional Reference Laboratory for Antimicrobial Resistance (NRL), Servicio Antimicrobianos, Instituto Nacional de Enfermedades Infecciosas, ANLIS Dr. Carlos G. Malbrán, Buenos Aires, Argentina.
  • Traglia GM; Departamento de Desarrollo Biotecnología, Instituto de Higiene, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay.
  • Martinez J; Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA.
  • Huang F; Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA.
  • Liu C; Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA.
  • Fernandez JS; Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA.
  • Lopez C; Instituto de Biología Molecular y Celular de Rosario (IBR, CONICET-UNR), Rosario, Argentina.
  • Gonzalez LJ; Instituto de Biología Molecular y Celular de Rosario (IBR, CONICET-UNR), Rosario, Argentina.
  • Albornoz E; Área Biofísica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Rosario, Argentina.
  • Corso A; National/Regional Reference Laboratory for Antimicrobial Resistance (NRL), Servicio Antimicrobianos, Instituto Nacional de Enfermedades Infecciosas, ANLIS Dr. Carlos G. Malbrán, Buenos Aires, Argentina.
  • Vila AJ; National/Regional Reference Laboratory for Antimicrobial Resistance (NRL), Servicio Antimicrobianos, Instituto Nacional de Enfermedades Infecciosas, ANLIS Dr. Carlos G. Malbrán, Buenos Aires, Argentina.
  • Bonomo RA; Instituto de Biología Molecular y Celular de Rosario (IBR, CONICET-UNR), Rosario, Argentina.
  • Ramirez MS; Área Biofísica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Rosario, Argentina.
Antimicrob Agents Chemother ; 64(5)2020 04 21.
Article em En | MEDLINE | ID: mdl-32122888
ABSTRACT
A 4-year surveillance of carbapenem-resistant Acinetobacter spp. isolates in Argentina identified 40 strains carrying blaNDM-1 Genome sequencing revealed that most were Acinetobacter baumannii, whereas seven represented other Acinetobacter spp. The A. baumannii genomes were closely related, suggesting recent spread. blaNDM-1 was located in the chromosome of A. baumannii strains and on a plasmid in non-A. baumannii strains. A resistance gene island carrying blaPER-7 and other resistance determinants was found on a plasmid in some A. baumannii strains.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Beta-Lactamases / Carbapenêmicos / Acinetobacter baumannii / Antibacterianos Limite: Humans País/Região como assunto: America do sul / Argentina Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Beta-Lactamases / Carbapenêmicos / Acinetobacter baumannii / Antibacterianos Limite: Humans País/Região como assunto: America do sul / Argentina Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos