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Demonstration of brain region-specific neuronal vulnerability in human iPSC-based model of familial Parkinson's disease.
Brazdis, Razvan-Marius; Alecu, Julian E; Marsch, Daniel; Dahms, Annika; Simmnacher, Katrin; Lörentz, Sandra; Brendler, Anna; Schneider, Yanni; Marxreiter, Franz; Roybon, Laurent; Winner, Beate; Xiang, Wei; Prots, Iryna.
Afiliação
  • Brazdis RM; Department of Stem Cell Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany.
  • Alecu JE; Department of Psychiatry and Psychotherapy, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany.
  • Marsch D; Department of Stem Cell Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany.
  • Dahms A; Institute of Biochemistry (Emil-Fischer-Center), Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany.
  • Simmnacher K; Institute of Biochemistry (Emil-Fischer-Center), Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany.
  • Lörentz S; Department of Stem Cell Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany.
  • Brendler A; Department of Stem Cell Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany.
  • Schneider Y; Department of Stem Cell Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany.
  • Marxreiter F; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany.
  • Roybon L; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany.
  • Winner B; Stem Cell Laboratory for CNS Disease Modeling, Department of Experimental Medical Science, Lund University, Lund 22184, Sweden.
  • Xiang W; Department of Stem Cell Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany.
  • Prots I; Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany.
Hum Mol Genet ; 29(7): 1180-1191, 2020 05 08.
Article em En | MEDLINE | ID: mdl-32160287
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Estresse Oxidativo / Alfa-Sinucleína / Células-Tronco Pluripotentes Induzidas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Estresse Oxidativo / Alfa-Sinucleína / Células-Tronco Pluripotentes Induzidas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha