Molecularly Engineered Nanobodies for Tunable Pharmacokinetics and Drug Delivery.

Glassman, Patrick M; Walsh, Landis R; Villa, Carlos H; Marcos-Contreras, Oscar A; Hood, Elizabeth D; Muzykantov, Vladimir R; Greineder, Colin F

Glassman, Patrick M; Walsh, Landis R; Villa, Carlos H; Marcos-Contreras, Oscar A; Hood, Elizabeth D; Muzykantov, Vladimir R; Greineder, Colin F.

Afiliação

Glassman PM; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Walsh LR; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Villa CH; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Marcos-Contreras OA; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Hood ED; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Muzykantov VR; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Greineder CF; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.

Bioconjug Chem ; 31(4): 1144-1155, 2020 04 15.

Article em En | MEDLINE | ID: mdl-32167754

Assuntos

Portadores de Fármacos/farmacocinética; Engenharia de Proteínas; Anticorpos de Domínio Único/genética; Anticorpos de Domínio Único/metabolismo; Animais; Transporte Biológico; Encéfalo/metabolismo; Portadores de Fármacos/metabolismo; Marcação por Isótopo; Camundongos; Anticorpos de Domínio Único/imunologia; Baço/metabolismo; Distribuição Tecidual; Molécula 1 de Adesão de Célula Vascular/imunologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Portadores de Fármacos / Engenharia de Proteínas / Anticorpos de Domínio Único Limite: Animals Idioma: En Revista: Bioconjug Chem Assunto da revista: BIOQUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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