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Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL.
Wierzbinska, Justyna A; Toth, Reka; Ishaque, Naveed; Rippe, Karsten; Mallm, Jan-Philipp; Klett, Lara C; Mertens, Daniel; Zenz, Thorsten; Hielscher, Thomas; Seifert, Marc; Küppers, Ralf; Assenov, Yassen; Lutsik, Pavlo; Stilgenbauer, Stephan; Roessner, Philipp M; Seiffert, Martina; Byrd, John; Oakes, Christopher C; Plass, Christoph; Lipka, Daniel B.
Afiliação
  • Wierzbinska JA; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Toth R; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
  • Ishaque N; The German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Rippe K; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Mallm JP; The German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Klett LC; The German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Mertens D; Division of Chromatin Networks, DKFZ, Heidelberg, Germany.
  • Zenz T; The German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Hielscher T; Division of Chromatin Networks, DKFZ, Heidelberg, Germany.
  • Seifert M; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
  • Küppers R; Division of Chromatin Networks, DKFZ, Heidelberg, Germany.
  • Assenov Y; The German Cancer Consortium (DKTK), Heidelberg, Germany.
  • Lutsik P; Mechanisms of Leukemogenesis, DKFZ, Heidelberg, Germany.
  • Stilgenbauer S; Experimental Hematology Lab, University Hospital Zurich, Zurich, Switzerland.
  • Roessner PM; Biostatistics, DKFZ, Heidelberg, Germany.
  • Seiffert M; Group Molecular Genetics, Essen University Hospital, Essen, Germany.
  • Byrd J; Group Molecular Genetics, Essen University Hospital, Essen, Germany.
  • Oakes CC; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Plass C; Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Lipka DB; Department of Internal Medicine, Ulm University, Ulm, Germany.
Genome Med ; 12(1): 29, 2020 03 18.
Article em En | MEDLINE | ID: mdl-32188505
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Linhagem da Célula / Epigenoma / Modelos Genéticos Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Revista: Genome Med Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Linhagem da Célula / Epigenoma / Modelos Genéticos Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Revista: Genome Med Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha