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Impaired proteolysis by SPPL2a causes CD74 fragment accumulation that can be recognized by anti-CD74 autoantibodies in human ankylosing spondylitis.
van Kempen, Tessa S; Leijten, Emmerik F A; Lindenbergh, Marthe F S; Nordkamp, Michel Olde; Driessen, Christoph; Lebbink, Robert-Jan; Baerlecken, Niklas; Witte, Torsten; Radstake, Timothy R D J; Boes, Marianne.
Afiliação
  • van Kempen TS; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Leijten EFA; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Lindenbergh MFS; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Nordkamp MO; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Driessen C; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Lebbink RJ; Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
  • Baerlecken N; Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Witte T; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Radstake TRDJ; Department of Oncology and Hematology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
  • Boes M; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Eur J Immunol ; 50(8): 1209-1219, 2020 08.
Article em En | MEDLINE | ID: mdl-32198923
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autoanticorpos / Espondilite Anquilosante / Antígenos de Diferenciação de Linfócitos B / Antígenos de Histocompatibilidade Classe II / Ácido Aspártico Endopeptidases / Proteólise Tipo de estudo: Etiology_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Immunol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autoanticorpos / Espondilite Anquilosante / Antígenos de Diferenciação de Linfócitos B / Antígenos de Histocompatibilidade Classe II / Ácido Aspártico Endopeptidases / Proteólise Tipo de estudo: Etiology_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Immunol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda