Mast cells and collagen fibrillogenesis.
Histochem Cell Biol
; 154(1): 21-40, 2020 Jul.
Article
em En
| MEDLINE
| ID: mdl-32222902
ABSTRACT
This article presents 20 combinations of histochemical stainings for the determination of mast cell co-localization with the fibrous component of the connective tissue in the fibrillogenesis course. Best results were obtained using metachromatic detection of mast cells in combination with silver or picro-fuchsin impregnation, staining with brilliant green using van Gieson staining, and a combination of aniline blue staining with neutral red. Proposed variants of histochemical protocols open up new opportunities to analyze the participation of mast cells in extracellular matrix remodeling of the tissue microenvironment in the course of adaptive and pathological processes. Results obtained expand the current theoretical views of the process of fibrillogenesis in the extracellular matrix. They also shed new light on the participation of mast cell secretion components in the molecular mechanisms of fiber formation.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Colágeno
/
Matriz Extracelular
/
Mastócitos
/
Músculos do Pescoço
Limite:
Animals
Idioma:
En
Revista:
Histochem Cell Biol
Assunto da revista:
CITOLOGIA
/
HISTOCITOQUIMICA
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Federação Russa