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A potent photoreactive general anesthetic with novel binding site selectivity for GABAA receptors.
Shalabi, Abdelrahman R; Yu, Zhiyi; Zhou, Xiaojuan; Jounaidi, Youssef; Chen, Hanwen; Dai, Jiajia; Kent, Daniel E; Feng, Hua-Jun; Forman, Stuart A; Cohen, Jonathan B; Bruzik, Karol S; Miller, Keith W.
Afiliação
  • Shalabi AR; Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL, 60612, USA.
  • Yu Z; Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, MA, 02115, USA. Electronic address: zhiyi_yu@sdu.edu.cn.
  • Zhou X; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, 32 Fruit Street, Boston, MA, 02114, USA.
  • Jounaidi Y; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, 32 Fruit Street, Boston, MA, 02114, USA.
  • Chen H; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, 32 Fruit Street, Boston, MA, 02114, USA. Electronic address: hanwen.chen@qq.com.
  • Dai J; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, 32 Fruit Street, Boston, MA, 02114, USA. Electronic address: Jiajiadai123@hotmail.com.
  • Kent DE; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, 32 Fruit Street, Boston, MA, 02114, USA; Department of Health Science, Northeastern University, 360 Huntington Ave, Boston, MA, 02115, USA.
  • Feng HJ; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, 32 Fruit Street, Boston, MA, 02114, USA.
  • Forman SA; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, 32 Fruit Street, Boston, MA, 02114, USA.
  • Cohen JB; Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, MA, 02115, USA.
  • Bruzik KS; Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL, 60612, USA.
  • Miller KW; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, 32 Fruit Street, Boston, MA, 02114, USA. Electronic address: k_miller@helix.mgh.harvard.edu.
Eur J Med Chem ; 194: 112261, 2020 May 15.
Article em En | MEDLINE | ID: mdl-32247113
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Propofol / Receptores de GABA-A / Anestésicos Gerais Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Propofol / Receptores de GABA-A / Anestésicos Gerais Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos