Emerging design strategies for constructing multiplex lateral flow test strip sensors.
Biosens Bioelectron
; 157: 112168, 2020 Jun 01.
Article
em En
| MEDLINE
| ID: mdl-32250938
ABSTRACT
Conventional lateral flow test strip (LFTS) sensors are insufficiently accurate and reliable due to their single-target detection with limited sample information in a single test. The increasing demand for the simultaneous determination of multiple analytes has recently been accelerating the rapid development of high-throughput and multiplexed LFTS sensing technologies. In this contribution, we systematically summarize the recent achievements on the design, development, and application of multiplexed LFTS sensors for improved rapid on-site diagnostics. The discussion focuses on emerging design strategies to increase multiplexing capacity for enhancing analytical efficiency and precision. As a proof-of-concept, several typical examples are presented. The advantages and disadvantages of such approaches are critically analyzed. Finally, we briefly discuss the current challenges and future perspectives.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fitas Reagentes
/
Técnicas Biossensoriais
/
Técnicas Analíticas Microfluídicas
/
Testes Imediatos
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Biosens Bioelectron
Assunto da revista:
BIOTECNOLOGIA
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
China