H2A Monoubiquitination Links Glucose Availability to Epigenetic Regulation of the Endoplasmic Reticulum Stress Response and Cancer Cell Death.

Zhang, Yilei; Shi, Jiejun; Liu, Xiaoguang; Xiao, Zhenna; Lei, Guang; Lee, Hyemin; Koppula, Pranavi; Cheng, Weijie; Mao, Chao; Zhuang, Li; Ma, Li; Li, Wei; Gan, Boyi

Zhang, Yilei; Shi, Jiejun; Liu, Xiaoguang; Xiao, Zhenna; Lei, Guang; Lee, Hyemin; Koppula, Pranavi; Cheng, Weijie; Mao, Chao; Zhuang, Li; Ma, Li; Li, Wei; Gan, Boyi.

Afiliação

Zhang Y; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Shi J; Department of Biological Chemistry, University of California, Irvine, Irvine, California.
Liu X; Division of Biostatistics, Dan L. Duncan Cancer Center and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas.
Xiao Z; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Lei G; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Lee H; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Koppula P; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Cheng W; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Mao C; The University of Texas MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, Texas.
Zhuang L; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Ma L; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Li W; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Gan B; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Cancer Res ; 80(11): 2243-2256, 2020 06 01.

Article em En | MEDLINE | ID: mdl-32273282

Assuntos

Estresse do Retículo Endoplasmático/genética; Glucose/metabolismo; Histonas/genética; Histonas/metabolismo; Neoplasias Renais/genética; Neoplasias Pulmonares/genética; Quinases Proteína-Quinases Ativadas por AMP; Animais; Proteínas de Ciclo Celular/antagonistas & inibidores; Proteínas de Ciclo Celular/metabolismo; Morte Celular/fisiologia; Linhagem Celular Tumoral; Epigênese Genética; Feminino; Regulação Neoplásica da Expressão Gênica; Glucose/administração & dosagem; Glucose/deficiência; Transportador de Glucose Tipo 1/antagonistas & inibidores; Transportador de Glucose Tipo 1/genética; Transportador de Glucose Tipo 1/metabolismo; Células HEK293; Xenoenxertos; Humanos; Neoplasias Renais/metabolismo; Neoplasias Renais/patologia; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/patologia; Camundongos; Camundongos Nus; Fosforilação; Complexo Repressor Polycomb 1/genética; Complexo Repressor Polycomb 1/metabolismo; Proteínas Quinases/genética; Proteínas Quinases/metabolismo; Ubiquitinação

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Histonas / Estresse do Retículo Endoplasmático / Glucose / Neoplasias Renais / Neoplasias Pulmonares Limite: Animals / Female / Humans Idioma: En Revista: Cancer Res Ano de publicação: 2020 Tipo de documento: Article

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