Platelet-Rich plasma as an effective alternative approach for improving endometrial receptivity - a clinical retrospective study.

ABSTRACT

OBJECTIVE: The aim of the present case series was to describe our experience with the use of PRP on patients with refractory thin endometria. METHODS: This retrospective analysis included 24 IVF cycles in which patients presenting different infertility factors received intrauterine PRP infusion prior to embryo transfer. Outcomes of interest were clinical and ongoing pregnancies, miscarriages, and births. RESULTS: 54% of the cycles in which PRP was employed resulted in ongoing gestation or birth; 12.5% of the cycles ended in miscarriages. CONCLUSION: Our data suggest that PRP improves intrauterine receptivity to embryo implantation, regardless of whether the endometrium reached the appropriate growth for embryo transfer.