LDL subclass lipidomics in atherogenic dyslipidemia: effect of statin therapy on bioactive lipids and dense LDL.

Chapman, M John; Orsoni, Alexina; Tan, Ricardo; Mellett, Natalie A; Nguyen, Anh; Robillard, Paul; Giral, Philippe; Thérond, Patrice; Meikle, Peter J

Chapman, M John; Orsoni, Alexina; Tan, Ricardo; Mellett, Natalie A; Nguyen, Anh; Robillard, Paul; Giral, Philippe; Thérond, Patrice; Meikle, Peter J.

Afiliação

Chapman MJ; Endocrinology Metabolism Division, Pitié-Salpetrière University Hospital, Sorbonne University and National Institute for Health and Medical Research (INSERM), Paris, France; Metabolomics Laboratory Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia. Electronic address: mailto:john.ch
Orsoni A; Service de Biochimie AP-HP, HU Paris-Saclay, Bicetre University Hospital, Le Kremlin Bicêtre and EA 7357, Paris-Saclay University, Chatenay-Malabry, France.
Tan R; Metabolomics Laboratory Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.
Mellett NA; Metabolomics Laboratory Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.
Nguyen A; Metabolomics Laboratory Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.
Robillard P; Endocrinology Metabolism Division, Pitié-Salpetrière University Hospital, Sorbonne University and National Institute for Health and Medical Research (INSERM), Paris, France.
Giral P; INSERM UMR1166 and Cardiovascular Prevention Units, ICAN-Institute of CardioMetabolism and Nutrition, AP-HP, Pitié-Salpetrière University Hospital, Paris, France.
Thérond P; Service de Biochimie AP-HP, HU Paris-Saclay, Bicetre University Hospital, Le Kremlin Bicêtre and EA 7357, Paris-Saclay University, Chatenay-Malabry, France.
Meikle PJ; Metabolomics Laboratory Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.

J Lipid Res ; 61(6): 911-932, 2020 06.

Article em En | MEDLINE | ID: mdl-32295829

Assuntos

Aterosclerose/complicações; Dislipidemias/tratamento farmacológico; Dislipidemias/metabolismo; Inibidores de Hidroximetilglutaril-CoA Redutases/farmacologia; Lipidômica; Lipoproteínas LDL/metabolismo; Dislipidemias/complicações; Feminino; Humanos; Inibidores de Hidroximetilglutaril-CoA Redutases/uso terapêutico; Masculino; Pessoa de Meia-Idade

Palavras-chave

ceramides; isopycnic density gradient ultracentrifugation; lipoprotein-associated phospholipase A2; liquid chromatography electrospray ionization-tandem mass spectrometry; low density lipoprotein; low density lipoprotein subclass heterogeneity; lysophosphatidylcholine; metabolic syndrome; pitavastatin calcium

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Hidroximetilglutaril-CoA Redutases / Aterosclerose / Dislipidemias / Lipidômica / Lipoproteínas LDL Limite: Female / Humans / Male / Middle aged Idioma: En Revista: J Lipid Res Ano de publicação: 2020 Tipo de documento: Article

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