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Laparoscopic Adjustable Gastric Banding-Should a Second Chance Be Given?
Leca, Bianca M; Khan, Uzma; Abraham, Jenny; Halder, Louise; Shuttlewood, Emma; Shah, Neha; Ellis, Hugh L; Aylwin, Simon J B; Barber, Thomas M; Menon, Vinod; Randeva, Harpal S; Dimitriadis, Georgios K.
Afiliação
  • Leca BM; Department of Endocrinology, Diabetes and Metabolism - WISDEM Centre, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, CV2 2DX, UK.
  • Khan U; Department of Endocrinology, Diabetes and Metabolism - WISDEM Centre, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, CV2 2DX, UK.
  • Abraham J; Department of Surgery, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, CV2 2DX, UK.
  • Halder L; Department of Dietetics, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, CV2 2DX, UK.
  • Shuttlewood E; Department of Surgery, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, CV2 2DX, UK.
  • Shah N; Department of Dietetics, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, CV2 2DX, UK.
  • Ellis HL; Department of Endocrinology and Metabolic Medicine, King's College Hospital NHS Foundation Trust, Denmark Hill, London, SE5 9RS, UK.
  • Aylwin SJB; Department of Endocrinology and Metabolic Medicine, King's College Hospital NHS Foundation Trust, Denmark Hill, London, SE5 9RS, UK.
  • Barber TM; Department of Endocrinology, Diabetes and Metabolism - WISDEM Centre, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, CV2 2DX, UK.
  • Menon V; Clinical Sciences Research Laboratories, University of Warwick Medical School, Coventry, CV2 2DX, UK.
  • Randeva HS; Department of Surgery, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, CV2 2DX, UK.
  • Dimitriadis GK; Clinical Sciences Research Laboratories, University of Warwick Medical School, Coventry, CV2 2DX, UK.
Obes Surg ; 30(8): 2913-2919, 2020 Aug.
Article em En | MEDLINE | ID: mdl-32304013
ABSTRACT

BACKGROUND:

Obesity is a chronic relapsing-remitting disease and a global pandemic, being associated with multiple comorbidities. Laparoscopic adjustable gastric banding (LAGB) is one of the safest surgical procedures used for the treatment of obesity, and even though its popularity has been decreasing over time, it still remains an option for a certain group of patients, producing considerable weight loss and improvement in obesity-associated comorbidities.

METHODS:

The aim of this study was to evaluate the impact of weight loss following LAGB on obesity-associated comorbidities, and to identify factors that could predict better response to surgery, and patient sub-groups exhibiting greatest benefit. A total of 99 severely obese patients (81.2% women, mean age 44.19 ± 10.94 years, mean body mass index (BMI) 51.84 ± 8.77 kg/m2) underwent LAGB in a single institution. Results obtained 1, 2, and 5 years postoperatively were compared with the pre-operative values using SPPS software version 20.

RESULTS:

A significant drop in BMI was recorded throughout the follow-up period, as well as in A1c and triglycerides, with greatest improvement seen 2 years after surgery (51.8 ± 8.7 kg/m2 vs 42.3 ± 9.2 kg/m2, p < 0.05, 55.5 ± 19.1 mmol/mol vs 45.8 ± 13.7 mmol/mol, p < 0.05, and 2.2 ± 1.7 mmol/l vs 1.5 ± 0.6 mmol/l). Better outcomes were seen in younger patients, with lower duration of diabetes before surgery, and lower pre-operative systolic blood pressure.

CONCLUSIONS:

Younger age, lower degree of obesity, and lower severity of comorbidities at the time of surgery can be important predictors of successful weight loss, making this group of patients the ideal candidates for LAGB.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Obesidade Mórbida / Gastroplastia / Laparoscopia Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Obes Surg Assunto da revista: METABOLISMO Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Obesidade Mórbida / Gastroplastia / Laparoscopia Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Obes Surg Assunto da revista: METABOLISMO Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido