Demonstration of biogenic amines and adrenergic innervation in uveal malignant melanomas by the histoflurometric method.
Invest Ophthalmol Vis Sci
; 16(5): 396-403, 1977 May.
Article
em En
| MEDLINE
| ID: mdl-323183
ABSTRACT
Clinical and histologic studies were performed on 25 patients with malignant melanomas of the ciliary body and choroid. Portions of fresh tumor were quick frozen and processed by the histofluorometric technique to demonstrate the presence of biogenic amines. Separate portions of each tumor were fixed and processed for routine light microscopy. Specific fluorescence was visible in 21 of 23 pigmented neoplasms. Catecholamine-induced fluorescence of biogenic amines was related to tumor cell type. In two amelanotic tumors no specific fluorescence was seen.
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Base de dados:
MEDLINE
Assunto principal:
Sistema Nervoso Simpático
/
Úvea
/
Doenças da Úvea
/
Aminas Biogênicas
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Neoplasias Oculares
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Melanoma
Limite:
Adult
/
Aged
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Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Invest Ophthalmol Vis Sci
Ano de publicação:
1977
Tipo de documento:
Article