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Repurposing approach identifies pitavastatin as a potent azole chemosensitizing agent effective against azole-resistant Candida species.
Eldesouky, Hassan E; Salama, Ehab A; Li, Xiaoyan; Hazbun, Tony R; Mayhoub, Abdelrahman S; Seleem, Mohamed N.
Afiliação
  • Eldesouky HE; Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, IN, 47907, USA.
  • Salama EA; Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, IN, 47907, USA.
  • Li X; Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, IN, 47907, USA.
  • Hazbun TR; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana, 47907, USA.
  • Mayhoub AS; Bindley Bioscience Center, Purdue University, West Lafayette, Indiana, 47906, USA.
  • Seleem MN; University of Science and Technology, Nanoscience Program, Zewail City of Science and Technology, October Gardens, 6th of October, Giza, 12578, Egypt. amayhoub@azhar.edu.eg.
Sci Rep ; 10(1): 7525, 2020 05 05.
Article em En | MEDLINE | ID: mdl-32372011
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinolinas / Candida / Farmacorresistência Fúngica / Reposicionamento de Medicamentos / Voriconazol / Antifúngicos Idioma: En Revista: Sci Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinolinas / Candida / Farmacorresistência Fúngica / Reposicionamento de Medicamentos / Voriconazol / Antifúngicos Idioma: En Revista: Sci Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos