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Ascites-derived ALDH+CD44+ tumour cell subsets endow stemness, metastasis and metabolic switch via PDK4-mediated STAT3/AKT/NF-κB/IL-8 signalling in ovarian cancer.
Jiang, Yu-Xin; Siu, Michelle Kwan-Yee; Wang, Jing-Jing; Mo, Xue-Tang; Leung, Thomas Ho-Yin; Chan, David Wai; Cheung, Annie Nga-Yin; Ngan, Hextan Yuen-Sheung; Chan, Karen Kar-Loen.
Afiliação
  • Jiang YX; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong.
  • Siu MK; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong.
  • Wang JJ; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong.
  • Mo XT; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong.
  • Leung TH; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong.
  • Chan DW; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong.
  • Cheung AN; Department of Pathology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong.
  • Ngan HY; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong.
  • Chan KK; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong. kklchan@hku.hk.
Br J Cancer ; 123(2): 275-287, 2020 07.
Article em En | MEDLINE | ID: mdl-32390009
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Interleucina-8 / Fator de Transcrição STAT3 / Piruvato Desidrogenase Quinase de Transferência de Acetil / Recidiva Local de Neoplasia Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Revista: Br J Cancer Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Hong Kong
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Interleucina-8 / Fator de Transcrição STAT3 / Piruvato Desidrogenase Quinase de Transferência de Acetil / Recidiva Local de Neoplasia Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Revista: Br J Cancer Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Hong Kong