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Structural optimization of HPMA copolymer-based dexamethasone prodrug for improved treatment of inflammatory arthritis.
Jia, Zhenshan; Zhao, Gang; Wei, Xin; Kong, Dexuan; Sun, Yuanyuan; Zhou, You; Lele, Subodh M; Fehringer, Edward V; Garvin, Kevin L; Goldring, Steven R; Wang, Dong.
Afiliação
  • Jia Z; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE 68198, USA.
  • Zhao G; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE 68198, USA.
  • Wei X; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE 68198, USA. Electronic address: x.wei@unmc.edu.
  • Kong D; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE 68198, USA; Clinical Pharmacokinetics Laboratory, China Pharmaceutical University, Nanjing 211198, China.
  • Sun Y; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE 68198, USA.
  • Zhou Y; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE 68198, USA; Department of Orthopedics, the Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
  • Lele SM; Department of Pathology and Microbiology, College of Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA.
  • Fehringer EV; Department of Orthopaedic Surgery and Rehabilitation, University of Nebraska Medical Center, Omaha, NE 68198, USA.
  • Garvin KL; Department of Orthopaedic Surgery and Rehabilitation, University of Nebraska Medical Center, Omaha, NE 68198, USA.
  • Goldring SR; Hospital for Special Surgery, New York, NY 10021, USA.
  • Wang D; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE 68198, USA; Department of Orthopaedic Surgery and Rehabilitation, University of Nebraska Medical Center, Omaha, NE 68198, USA. Electronic address: dwang@unmc.edu.
J Control Release ; 324: 560-573, 2020 08 10.
Article em En | MEDLINE | ID: mdl-32445658
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Experimental / Pró-Fármacos Limite: Animals Idioma: En Revista: J Control Release Assunto da revista: FARMACOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Experimental / Pró-Fármacos Limite: Animals Idioma: En Revista: J Control Release Assunto da revista: FARMACOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos