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Discovery of secondary sulphonamides as IDO1 inhibitors with potent antitumour effects in vivo.
Ge, Shushan; Zhong, Haiqing; Ma, Xuewei; Zheng, Yingbo; Zou, Yi; Wang, Fang; Wang, Yan; Hu, Yue; Li, Yuezhen; Liu, Wen; Guo, Wenjie; Xu, Qiang; Lai, Yisheng.
Afiliação
  • Ge S; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Drug Discovery, China Pharmaceutical University, Nanjing, PR China.
  • Zhong H; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, PR China.
  • Ma X; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Drug Discovery, China Pharmaceutical University, Nanjing, PR China.
  • Zheng Y; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Drug Discovery, China Pharmaceutical University, Nanjing, PR China.
  • Zou Y; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Drug Discovery, China Pharmaceutical University, Nanjing, PR China.
  • Wang F; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Drug Discovery, China Pharmaceutical University, Nanjing, PR China.
  • Wang Y; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, PR China.
  • Hu Y; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, PR China.
  • Li Y; Department of Organic Chemistry, School of Science, China Pharmaceutical University, Nanjing, PR China.
  • Liu W; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, PR China.
  • Guo W; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, PR China.
  • Xu Q; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, PR China.
  • Lai Y; State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Drug Discovery, China Pharmaceutical University, Nanjing, PR China.
J Enzyme Inhib Med Chem ; 35(1): 1240-1257, 2020 Dec.
Article em En | MEDLINE | ID: mdl-32466694
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfonamidas / Inibidores Enzimáticos / Indolamina-Pirrol 2,3,-Dioxigenase / Antineoplásicos Limite: Animals / Humans / Male Idioma: En Revista: J Enzyme Inhib Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfonamidas / Inibidores Enzimáticos / Indolamina-Pirrol 2,3,-Dioxigenase / Antineoplásicos Limite: Animals / Humans / Male Idioma: En Revista: J Enzyme Inhib Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2020 Tipo de documento: Article