TNFAIP8 influences the motor function in mice after spinal cord injury (SCI) through meditating inflammation dependent on AKT.

Xue, Wen; Tan, Wei; Dong, Longjia; Tang, Qian; Yang, Feng; Shi, Xuexing; Jiang, Dianming; Qian, Yaowen

Xue, Wen; Tan, Wei; Dong, Longjia; Tang, Qian; Yang, Feng; Shi, Xuexing; Jiang, Dianming; Qian, Yaowen.

Afiliação

Xue W; Department of Orthopedics, Gansu Provincial Hospital, Lanzhou, 730000, China.
Tan W; Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Dong L; Department of Orthopedics, The Affiliated Baiyun Hospital of Guizhou Medical University, Guiyang, 550058, China.
Tang Q; Department of Orthopedics, The Affiliated Baiyun Hospital of Guizhou Medical University, Guiyang, 550058, China.
Yang F; Department of Orthopedics, The Affiliated Hospital of Guizhou Medical University, Guiyang, 550001, China.
Shi X; Department of Orthopedics, The Affiliated Baiyun Hospital of Guizhou Medical University, Guiyang, 550058, China.
Jiang D; Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. Electronic address: dingjm816@foxmail.com.
Qian Y; Department of Orthopedics, Gansu Provincial Hospital, Lanzhou, 730000, China. Electronic address: qyw2218@163.com.

Biochem Biophys Res Commun ; 528(1): 234-241, 2020 07 12.

Article em En | MEDLINE | ID: mdl-32487318

Assuntos

Inflamação/patologia; Atividade Motora; Proteínas Proto-Oncogênicas c-akt/metabolismo; Traumatismos da Medula Espinal/metabolismo; Traumatismos da Medula Espinal/fisiopatologia; Animais; Proteínas Reguladoras de Apoptose/deficiência; Proteínas Reguladoras de Apoptose/metabolismo; Linhagem Celular; Ativação Enzimática/efeitos dos fármacos; Feminino; Lipopolissacarídeos/farmacologia; Camundongos Endogâmicos C57BL; Regulação para Cima/efeitos dos fármacos

Palavras-chave

Inflammation; IκBα/NF-κB; PI3K/AKT; Spinal cord injury (SCI); TNFAIP8

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Traumatismos da Medula Espinal / Proteínas Proto-Oncogênicas c-akt / Inflamação / Atividade Motora Limite: Animals Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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