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Avicin G is a potent sphingomyelinase inhibitor and blocks oncogenic K- and H-Ras signaling.
Garrido, Christian M; Henkels, Karen M; Rehl, Kristen M; Liang, Hong; Zhou, Yong; Gutterman, Jordan U; Cho, Kwang-Jin.
Afiliação
  • Garrido CM; Department of Biochemistry and Molecular Biology, School of Boonshoft Medical School, Wright State University, Dayton, OH, 45435, United States.
  • Henkels KM; Department of Biochemistry and Molecular Biology, School of Boonshoft Medical School, Wright State University, Dayton, OH, 45435, United States.
  • Rehl KM; Department of Biochemistry and Molecular Biology, School of Boonshoft Medical School, Wright State University, Dayton, OH, 45435, United States.
  • Liang H; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, 77030, United States.
  • Zhou Y; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, 77030, United States.
  • Gutterman JU; Department of Systems Biology, The University of Texas M. D. Anderson Cancer Center, Houston, TX, 77030, United States.
  • Cho KJ; Department of Biochemistry and Molecular Biology, School of Boonshoft Medical School, Wright State University, Dayton, OH, 45435, United States. kwang-jin.cho@wright.edu.
Sci Rep ; 10(1): 9120, 2020 06 04.
Article em En | MEDLINE | ID: mdl-32499517

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Saponinas / Esfingomielina Fosfodiesterase / Proteínas ras Limite: Animals / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Saponinas / Esfingomielina Fosfodiesterase / Proteínas ras Limite: Animals / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos