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Notch signalling drives synovial fibroblast identity and arthritis pathology.
Wei, Kevin; Korsunsky, Ilya; Marshall, Jennifer L; Gao, Anqi; Watts, Gerald F M; Major, Triin; Croft, Adam P; Watts, Jordan; Blazar, Philip E; Lange, Jeffrey K; Thornhill, Thomas S; Filer, Andrew; Raza, Karim; Donlin, Laura T; Siebel, Christian W; Buckley, Christopher D; Raychaudhuri, Soumya; Brenner, Michael B.
Afiliação
  • Wei K; Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Korsunsky I; Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Marshall JL; Center for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.
  • Gao A; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Watts GFM; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
  • Major T; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Croft AP; Rheumatology Research Group, Institute for Inflammation and Ageing, NIHR Birmingham Biomedical Research Center and Clinical Research Facility, University of Birmingham, Queen Elizabeth Hospital, Birmingham, UK.
  • Watts J; Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Blazar PE; Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Lange JK; Rheumatology Research Group, Institute for Inflammation and Ageing, NIHR Birmingham Biomedical Research Center and Clinical Research Facility, University of Birmingham, Queen Elizabeth Hospital, Birmingham, UK.
  • Thornhill TS; Rheumatology Research Group, Institute for Inflammation and Ageing, NIHR Birmingham Biomedical Research Center and Clinical Research Facility, University of Birmingham, Queen Elizabeth Hospital, Birmingham, UK.
  • Filer A; Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Raza K; Department of Orthopedic Surgery, Brigham and Women's Hospital, Boston, MA, USA.
  • Donlin LT; Department of Orthopedic Surgery, Brigham and Women's Hospital, Boston, MA, USA.
  • Siebel CW; Rheumatology Research Group, Institute for Inflammation and Ageing, NIHR Birmingham Biomedical Research Center and Clinical Research Facility, University of Birmingham, Queen Elizabeth Hospital, Birmingham, UK.
  • Buckley CD; Rheumatology Research Group, Institute for Inflammation and Ageing, NIHR Birmingham Biomedical Research Center and Clinical Research Facility, University of Birmingham, Queen Elizabeth Hospital, Birmingham, UK.
  • Raychaudhuri S; Arthritis and Tissue Degeneration, Hospital for Special Surgery, New York, NY, USA.
Nature ; 582(7811): 259-264, 2020 06.
Article em En | MEDLINE | ID: mdl-32499639
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Membrana Sinovial / Transdução de Sinais / Fibroblastos / Receptor Notch3 Limite: Animals / Humans / Male Idioma: En Revista: Nature Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Membrana Sinovial / Transdução de Sinais / Fibroblastos / Receptor Notch3 Limite: Animals / Humans / Male Idioma: En Revista: Nature Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos