A Novel Particulate Delivery System Based on Antigen-Zn<sup>2+</sup> Coordination Interactions Enhances Stability and Cellular Immune Response of Inactivated Foot and Mouth Disease Virus.

Li, Shuai; Yang, Yanli; Lin, Xuan; Li, Zhengjun; Ma, Guanghui; Su, Zhiguo; Zhang, Songping

A Novel Particulate Delivery System Based on Antigen-Zn²⁺ Coordination Interactions Enhances Stability and Cellular Immune Response of Inactivated Foot and Mouth Disease Virus.

Li, Shuai; Yang, Yanli; Lin, Xuan; Li, Zhengjun; Ma, Guanghui; Su, Zhiguo; Zhang, Songping.

Afiliação

Li S; State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
Yang Y; University of Chinese Academy of Sciences, Beijing 100049, China.
Lin X; State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
Li Z; State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
Ma G; University of Chinese Academy of Sciences, Beijing 100049, China.
Su Z; State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.
Zhang S; State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China.

Mol Pharm ; 17(8): 2952-2963, 2020 08 03.

Article em En | MEDLINE | ID: mdl-32539415

Assuntos

Antígenos Virais/química; Antígenos Virais/imunologia; Vírus da Febre Aftosa/imunologia; Imunidade Celular/imunologia; Vacinas de Produtos Inativados/imunologia; Zinco/química; Adjuvantes Imunológicos/farmacologia; Animais; Linhagem Celular; Cricetinae; Citocinas/imunologia; Sistemas de Liberação de Medicamentos/métodos; Feminino; Febre Aftosa/imunologia; Imunidade Humoral/imunologia; Memória Imunológica/imunologia; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Endogâmicos C57BL; Linfócitos T/imunologia; Vacinas Virais/imunologia

Palavras-chave

cellular immunity; chitosan particles; coordination binding; foot and mouth disease virus; thermal stability

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Zinco / Vacinas de Produtos Inativados / Vírus da Febre Aftosa / Imunidade Celular / Antígenos Virais Limite: Animals Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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