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WT1 facilitates the self-renewal of leukemia-initiating cells through the upregulation of BCL2L2: WT1-BCL2L2 axis as a new acute myeloid leukemia therapy target.
Zhou, Bin; Jin, Xianghong; Jin, Weiwei; Huang, Xingzhou; Wu, Yanfei; Li, Haiying; Zhu, Weijian; Qin, Xiaoyi; Ye, Haige; Gao, Shenmeng.
Afiliação
  • Zhou B; Laboratory of Internal Medicine, The First Affiliated Hospital of Wenzhou Medical University, 1 Xuefubei Street, Ouhai District, Wenzhou, 325000, Zhejiang, China.
  • Jin X; Department of Hematology, The First Affiliated Hospital of Wenzhou Medical University, 1 Xuefubei Street, Ouhai District, Wenzhou, 325000, Zhejiang, China.
  • Jin W; Department of Obstetrics and Gynecology, Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine, Wenzhou, 325000, Zhejiang, China.
  • Huang X; Laboratory of Internal Medicine, The First Affiliated Hospital of Wenzhou Medical University, 1 Xuefubei Street, Ouhai District, Wenzhou, 325000, Zhejiang, China.
  • Wu Y; Laboratory of Internal Medicine, The First Affiliated Hospital of Wenzhou Medical University, 1 Xuefubei Street, Ouhai District, Wenzhou, 325000, Zhejiang, China.
  • Li H; Laboratory of Internal Medicine, The First Affiliated Hospital of Wenzhou Medical University, 1 Xuefubei Street, Ouhai District, Wenzhou, 325000, Zhejiang, China.
  • Zhu W; Laboratory of Internal Medicine, The First Affiliated Hospital of Wenzhou Medical University, 1 Xuefubei Street, Ouhai District, Wenzhou, 325000, Zhejiang, China.
  • Qin X; Department of Hematology, The First Affiliated Hospital of Wenzhou Medical University, 1 Xuefubei Street, Ouhai District, Wenzhou, 325000, Zhejiang, China.
  • Ye H; Department of Hematology, The First Affiliated Hospital of Wenzhou Medical University, 1 Xuefubei Street, Ouhai District, Wenzhou, 325000, Zhejiang, China. haigeye@sina.com.
  • Gao S; Laboratory of Internal Medicine, The First Affiliated Hospital of Wenzhou Medical University, 1 Xuefubei Street, Ouhai District, Wenzhou, 325000, Zhejiang, China. gaoshenmeng77@wzhospital.cn.
J Transl Med ; 18(1): 254, 2020 06 24.
Article em En | MEDLINE | ID: mdl-32580769
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Leucemia Mieloide Aguda / Proteínas Reguladoras de Apoptose Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Transl Med Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Leucemia Mieloide Aguda / Proteínas Reguladoras de Apoptose Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Transl Med Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China