Use of telephone helpline data for syndromic surveillance of adverse events following immunization in Australia: A retrospective study, 2009 to 2017.
Vaccine
; 38(34): 5525-5531, 2020 07 22.
Article
em En
| MEDLINE
| ID: mdl-32593607
ABSTRACT
BACKGROUND:
The increasing availability of electronic healthcare data offers an opportunity to enhance adverse events following immunisation (AEFI) signal monitoring in near real-time.AIM:
To evaluate the potential use of telephone helpline data to augment the existing AEFI surveillance system in Victoria, Australia.METHODS:
Anonymised telephone helpline call data were extracted between 2009 and 2017. For comparison, we included AEFI reports to the Victorian enhanced passive surveillance system, SAEFVIC-"Surveillance of Adverse Events Following Vaccination In the Community". The temporal pattern cross-correlation coefficient at different time lags was estimated as a measure of timeliness evaluation. Historically known AEFI signals in 2010 and 2015 were examined using the Farrington statistical signal detection algorithm.RESULT:
During the study period, overall, the telephone helpline centre received 2,005,226 calls. Of these, 0.68% (13,719) were AEFI-related. In the same period, SAEFVIC received 10,367 AEFI related reports. Cross-correlation analysis, generally, showed that the two datasets were moderately correlated (r = 0.4) at a negative lag of 1 week. For individual years, the cross-correlation coefficient was highest (r = 0.66) in 2010 with the telephone helpline data leading by 2 weeks. Our analysis indicated the 2010 reported incidence of febrile convulsions and the 2015 reported increased allergic-related reactions following seasonal influenza vaccination three weeks and one week earlier respectively.CONCLUSION:
Telephone helpline data was able to detect an increased rate of AEFI earlier than the enhanced passive AEFI surveillance system. This dataset offers a valuable and near real-time component of an integrated AEFI early signal detection system in Australia.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Sistemas de Notificação de Reações Adversas a Medicamentos
/
Vigilância de Evento Sentinela
Tipo de estudo:
Observational_studies
/
Screening_studies
País/Região como assunto:
Oceania
Idioma:
En
Revista:
Vaccine
Ano de publicação:
2020
Tipo de documento:
Article