Chemical constituents from the stems of Acanthopanax senticosus with their inhibitory activity on α-glucosidase.
J Asian Nat Prod Res
; 23(8): 803-808, 2021 Aug.
Article
em En
| MEDLINE
| ID: mdl-32614676
ABSTRACT
A new aurone named (2Z)-2-[(4'-hydroxy-3'-methoxyphenyl) methylene]-6-methoxy-7-prenyl-3(2H)-benzofurane (1), together with five known compounds (2-6), were isolated from EtOAc-soluble extract of the stems of Acanthopanax senticosus. The chemical structures were elucidated on the basis of spectroscopic analyses. All isolates were evaluated for in vitro inhibitory activity on α-glucosidase. Among them, compounds 1 and 4 were found to exhibit moderate inhibitory activity on α-glucosidase with IC50 value of 64.1 ± 1.2 and 48.9 ± 1.1 µM, respectively.[Formula see text].
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Eleutherococcus
Idioma:
En
Revista:
J Asian Nat Prod Res
Assunto da revista:
BOTANICA
/
QUIMICA
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
China