[Induction of the traits of the differentiated T-cell phenotype in the blast cells of patients with acute lymphoblastic leukemia. I. The expression of T-cell markers as affected by different inducers]. / Induktsiia nekotorykh priznakov differentsirovannogo T-kletochnogo fenotipa u blastnykh kletok bol'nykh ostrym limfoblastnym leikozom. I. Ekspressiia T-kletochnykh markerov pod vliianiem razlichnykh induktorov.
Tsitologiia
; 30(6): 745-50, 1988 Jun.
Article
em Ru
| MEDLINE
| ID: mdl-3262948
ABSTRACT
The expression of T-lymphocyte markers has been demonstrated by blast cells of patients with non-T, non-B and pre-T-cell acute lymphoblastic leukaemia (ALL). The main inducing agent is phytohemagglutinin (PHA). Its action was enhanced when combined with phorbol ether (TPA) or ouabain. Dimethylsulfoxide, ouabain and concanavalin A had no similar inducing effect. TPA caused the expression of some T-cell markers revealed by monoclonal antibodies but had only a little inducing effect to E-receptor.
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Base de dados:
MEDLINE
Assunto principal:
Linfócitos T
/
Antígenos de Diferenciação de Linfócitos T
/
Transformação Celular Neoplásica
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
/
Mitógenos
Limite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Humans
Idioma:
Ru
Revista:
Tsitologiia
Ano de publicação:
1988
Tipo de documento:
Article