Sugar-sweetened beverage consumption and risk of hyperuricemia: a longitudinal analysis of the Health Workers Cohort Study participants in Mexico.
Am J Clin Nutr
; 112(3): 652-660, 2020 09 01.
Article
em En
| MEDLINE
| ID: mdl-32644154
ABSTRACT
BACKGROUND:
The elevated consumption of sugar-sweetened beverages (SSBs) in Mexico is an important public health concern. However, the association between SSB consumption and hyperuricemia has been scarcely studied and not well documented.OBJECTIVES:
To prospectively evaluate the association between SSB consumption and risk of hyperuricemia in Mexican adults.METHODS:
A longitudinal analysis was conducted using data from the Health Workers Cohort Study. Participants were followed from 2004 to 2018, with measurements every 6 y. The analysis sample consisted of 1300 adults, aged 18 to 85 y. SSB consumption during the previous year was evaluated through a semiquantitative FFQ. Hyperuricemia was defined as a concentration of uric acid ≥7.0 mg/dL in men and ≥5.7 mg/dL in women. We evaluated the association of interest using 2 methodologies fixed-effects logistic regression and generalized estimating equations (GEEs). Potential confounders were included in both approaches.RESULTS:
At baseline, median intake of SSBs was 472.1 mL/wk (IQR 198.8-1416.4 mL/wk), and 233 participants had hyperuricemia. Uric acid was higher in participants with an SSB intake ≥7 servings/wk, compared with those with an intake <1 serving/wk (P < 0.001). Participants who changed from the lowest to the highest category of servings consumption experienced 2.6 increased odds of hyperuricemia (95% CI 1.27, 5.26). Results from the GEE model indicated the odds of hyperuricemia increased by 44% (OR=1.44; 95% CI 1.13, 1.84) in the 2-6 servings/wk group, and by 89% (OR=1.89; 95% CI 1.39, 2.57) in the ≥7 servings/wk categories, compared with the <1 serving/wk category. Diet soft drinks were not associated with hyperuricemia.CONCLUSIONS:
Our results suggest that the consumption of SSBs is associated with an increased risk of hyperuricemia in Mexican adults, but diet soft drink consumption is not, which supports the need to strengthen existing recommendations to reduce the intake of SSBs.The Health Workers Cohort Study (HWCS) has been approved by the Institutional Review Board of the Mexican Social Security Institute (12CEI 09 006 14), and the National Institute of Public Health of Mexico (13CEI 17 007 36).Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Hiperuricemia
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Bebidas Adoçadas com Açúcar
Tipo de estudo:
Etiology_studies
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Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
País/Região como assunto:
Mexico
Idioma:
En
Revista:
Am J Clin Nutr
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
México