Cerebral palsy: Aetiology, pathophysiology and therapeutic interventions.
Clin Exp Pharmacol Physiol
; 47(12): 1891-1901, 2020 12.
Article
em En
| MEDLINE
| ID: mdl-32662125
ABSTRACT
Cerebral palsy (CP) is the most common non-progressive neurodevelopmental disorder in which the impairment of motor and posture functions occurs. This condition may be present in many different clinical spectra. Various aetiological and risk factors play a crucial role in the causation of CP. In various cases, the causes of CP may not be apparent. Interruption in the supply of oxygen to the fetus or brain asphyxia was considered to be the main causative factor explaining CP. Antenatal, perinatal, and postnatal factors could be involved in the origin of CP. Understanding its pathophysiology is also crucial for developing preventive and protective strategies. A major advancement in the brain stimulation techniques has emerged as a promising status in diagnostic and interventional approaches. This review provides a brief explanation about the various aetiological factors, pathophysiology, and recent therapeutic approaches in the treatment of cerebral palsy.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Paralisia Cerebral
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Female
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Humans
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Newborn
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Pregnancy
Idioma:
En
Revista:
Clin Exp Pharmacol Physiol
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Índia