Research Progress on MicroRNA in Forensic Medicine as Molecular Markers.
Fa Yi Xue Za Zhi
; 36(3): 374-378, 2020 Jun.
Article
em En, Zh
| MEDLINE
| ID: mdl-32705853
ABSTRACT
ABSTRACT MicroRNA ï¼miRNAï¼ belongs to a class of endogenous non-coding small RNA molecules with a length of 18-24 nucleotides. The expression of miRNA is highly conservative, has time sequence and is highly tissue-specific. MiRNA could not be easily degraded by ribonuclease, and is resistant to changes in environmental factors such as temperature and pH value. Moreover, miRNA can even be detected in corrupt tissue. As a result, miRNA has broad application prospects in many fields of forensic medicine such as source identification of body fluid and estimation of cause of death. This article briefly summarizes the application of miRNA in forensic practice, such as body fluid identification, determination of postmortem interval and cause of death analysis.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Marcadores Genéticos
/
MicroRNAs
/
Medicina Legal
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
/
Zh
Revista:
Fa Yi Xue Za Zhi
Assunto da revista:
JURISPRUDENCIA
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
China