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Anti-stress effects of rosemary (Rosmarinus officinalis L.) leaf extract on intestinal goblet cells and immobility of forced-swimming test in BALB/c mice.
Kayashima, Tomoko; Nagao, Koji; Umino, Mituki; Kaikiri, Hiroko; Shibata, Sachi; Matsubara, Kiminori.
Afiliação
  • Kayashima T; Department of School Education Course, Faculty of Education, Saga University , Saga, Japan.
  • Nagao K; Department of Biological Resource Science, Applied Biochemistry and Food Science Course, Faculty of Agriculture, Saga University , Saga, Japan.
  • Umino M; Department of Human Life Sciences Education, Graduate School of Education, Hiroshima University , Hiroshima, Japan.
  • Kaikiri H; Department of Community Human Life, Hiroshima Bunka Gakuen Two-Year College , Hiroshima, Japan.
  • Shibata S; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University , Hiroshima, Japan.
  • Matsubara K; Department of Human Life Sciences Education, Graduate School of Education, Hiroshima University , Hiroshima, Japan.
Biosci Biotechnol Biochem ; 84(11): 2385-2389, 2020 Nov.
Article em En | MEDLINE | ID: mdl-32741270
We investigated the anti-stress effect of rosemary (Rosmarinus officinalis L.) leaf extract (RLE) on restraint-stressed mice and found that RLE alleviated decreases in the number of intestinal goblet cells and amount of hepatic triglycerides. It also decreased the immobility time in the forced-swimming test and activation of microglia in the brain, suggesting that RLE has beneficial effects on stress-induced dysfunctions.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estresse Psicológico / Extratos Vegetais / Folhas de Planta / Células Caliciformes / Rosmarinus Limite: Animals Idioma: En Revista: Biosci Biotechnol Biochem Assunto da revista: BIOQUIMICA / BIOTECNOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estresse Psicológico / Extratos Vegetais / Folhas de Planta / Células Caliciformes / Rosmarinus Limite: Animals Idioma: En Revista: Biosci Biotechnol Biochem Assunto da revista: BIOQUIMICA / BIOTECNOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão